Novel KMT2A-ATP5L gene fusion in a young adult with rapidly progressive Ph-like t(9;12) acute B lymphoblastic leukemia

• 主要な著者: Cyrus Parsa, D.O (著者), Amanda Thompson (著者), Robert Orlando, M.D., Ph.D (著者), Ravin Rupani, M.D (著者), Jin Guo, M.D (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2020-06-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Chromosomal abnormalities involving 11q23 with Lysine [K]specific MethylTransferase 2A (KMT2A) gene rearrangement are common among children with aggressive acute leukemias. In KMT2A-rearranged adult Acute Lymphoblastic Leukemia (ALL), five translocation partner genes account for greater than 95% of...