Antioxidative NAC-Loaded Silk Nanoparticles with Opening Mucosal Tight Junctions for Nasal Drug Delivery: An In Vitro and In Vivo Study
Using nasal routes to deliver drugs to the brain using multifunctional nanoparticles (NPs) to bypass the blood-brain barrier (BBB) might enhance the delivery efficacy. Anti-oxidative N-Acetyl-L-cysteine (NAC)-loaded silk fibroin (SF/NAC) NPs are produced, characterized and studied as a potential del...
Saved in:
Main Authors: | Tze-Wen Chung (Author), Ting-Ya Wu (Author), Zheng-Yu Siah (Author), Der-Zen Liu (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2022-06-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The Tight Junction and Its Proteins More Than Just a Barrier
Published: (2020) -
VEGF-mediated tight junctions pathological fenestration enhances doxorubicin-loaded glycolipid-like nanoparticles traversing BBB for glioblastoma-targeting therapy
by: Lijuan Wen, et al.
Published: (2017) -
Tight junctions in Hailey-Hailey and Darier's diseases
by: Laura Raiko, et al.
Published: (2009) -
Transcriptional Regulators of Claudins in Epithelial Tight Junctions
by: Niamat Khan, et al.
Published: (2015) -
Role of Tight Junctions and Their Protein Expression in Atopic Dermatitis
by: Kunwar Namrata, et al.
Published: (2021)