Chalcones Isolated from <i>Arrabidaea brachypoda</i> Flowers as Inhibitors of NorA and MepA Multidrug Efflux Pumps of <i>Staphylococcus aureus</i>

• Main Authors: Luís Mário Rezende-Júnior (Author), Leila Maria de Sousa Andrade (Author), Antonio Linkoln Alves Borges Leal (Author), Avilnete Belem de Souza Mesquita (Author), Ana Lurdes Portela de Araújo dos Santos (Author), José de Sousa Lima Neto (Author), José Pinto Siqueira-Júnior (Author), Carlos Emídio Sampaio Nogueira (Author), Glenn William Kaatz (Author), Henrique Douglas Melo Coutinho (Author), Natália Martins (Author), Cláudia Quintino da Rocha (Author), Humberto Medeiros Barreto (Author)
• Format: Book
• Published: MDPI AG, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bacterial resistance to antibiotics has become a public health issue around the world. The present study aimed to evaluate the antibacterial activity of chalcones isolated from flowers of <i>Arrabidaea brachypoda</i>, and their potential as efflux pump inhibitors of <i>Staphylococc...