Mannose-Coated Reconstituted Lipoprotein Nanoparticles for the Targeting of Tumor-Associated Macrophages: Optimization, Characterization, and In Vitro Evaluation of Effectiveness

• Main Authors: Akpedje S. Dossou (Author), Morgan E. Mantsch (Author), Ammar Kapic (Author), William L. Burnett (Author), Nirupama Sabnis (Author), Jeffery L. Coffer (Author), Rance E. Berg (Author), Rafal Fudala (Author), Andras G. Lacko (Author)
• Format: Book
• Published: MDPI AG, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Reconstituted high-density lipoprotein nanoparticles (rHDL NPs) have been utilized as delivery vehicles to a variety of targets, including cancer cells. However, the modification of rHDL NPs for the targeting of the pro-tumoral tumor-associated macrophages (TAMs) remains largely unexplored. The pres...