Hemophagocytic lymphohistocytosis in trisomy 21: successful treatment with interferon inhibition
Abstract Background Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition of immune dysregulation primarily driven by the cytokine interferon gamma. It can be either a genetic or acquired disorder associated with infection, malignancy, and rheumatologic disorders. Trisomy 21 can e...
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BMC,
2022-11-01T00:00:00Z.
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