Aurantio-obtusin relaxes systemic arteries through endothelial PI3K/AKT/eNOS-dependent signaling pathway in rats

• Egile Nagusiak: Shuzhen Li (Egilea), Qian Li (Egilea), Xinyu Lv (Egilea), Lin Liao (Egilea), Weiwei Yang (Egilea), Shanshan Li (Egilea), Ping Lu (Egilea), Daling Zhu (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2015-07-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Aurantio-obtusin is a natural effective compound isolated from Semen Cassiae, which possesses hypotensive and hypolipidemic effects. Although its hypotensive effect have been clarified, mechanisms Aurantio-obtusin relaxes systemic arteries remain unclear. This study was to investigate effects and me...