In Vitro-In Vivo Correlation (IVIVC) Population Modeling for the In Silico Bioequivalence of a Long-Acting Release Formulation of Progesterone

• मुख्य लेखकों: Elena M. Tosca (लेखक), Maurizio Rocchetti (लेखक), Elena Pérez (लेखक), Conchi Nieto (लेखक), Paolo Bettica (लेखक), Jaime Moscoso del Prado (लेखक), Paolo Magni (लेखक), Giuseppe De Nicolao (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Health authorities carefully evaluate any change in the batch manufacturing process of a drug before and after regulatory approval. In the absence of an adequate in vitro-in vivo correlation (Level A IVIVC), an in vivo bioequivalence (BE) study is frequently required, increasing the cost and time of...