HIF1α-Induced Glycolysis Metabolism Is Essential to the Activation of Inflammatory Macrophages

• Principais autores: Ting Wang (Autor), Huiying Liu (Autor), Guan Lian (Autor), Song-Yang Zhang (Autor), Xian Wang (Autor), Changtao Jiang (Autor)
• Formato: Livro
• Publicado em: Hindawi Limited, 2017-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Hypoxia-inducible factor (HIF) 1α is a metabolic regulator that plays an important role in immunologic responses. Previous studies have demonstrated that HIF1α participates in the M1 polarization of macrophages. To clarify the mechanism of HIF1α-induced polarization of M1 macrophage, myeloid-specifi...