HIF1α-Induced Glycolysis Metabolism Is Essential to the Activation of Inflammatory Macrophages

• Main Authors: Ting Wang (Author), Huiying Liu (Author), Guan Lian (Author), Song-Yang Zhang (Author), Xian Wang (Author), Changtao Jiang (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hypoxia-inducible factor (HIF) 1α is a metabolic regulator that plays an important role in immunologic responses. Previous studies have demonstrated that HIF1α participates in the M1 polarization of macrophages. To clarify the mechanism of HIF1α-induced polarization of M1 macrophage, myeloid-specifi...