A Role for CD154, the CD40 Ligand, in Granulomatous Inflammation

• Main Authors: Julien Villeneuve (Author), Alexis Desmoulière (Author), Antoine Dewitte (Author), Nelly Bordeau (Author), Pierre Costet (Author), Laia Bassaganyas (Author), Jean-Christophe Fricain (Author), Jean Ripoche (Author), Sébastien Lepreux (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Granulomatous inflammation is a distinctive form of chronic inflammation in which predominant cells include macrophages, epithelioid cells, and multinucleated giant cells. Mechanisms regulating granulomatous inflammation remain ill-understood. CD154, the ligand of CD40, is a key mediator of inflamma...