Characterization of B- and T-Cell Compartment and B-Cell Related Factors Belonging to the TNF/TNFR Superfamily in Patients With Clinically Active Systemic Lupus Erythematosus: Baseline BAFF Serum Levels Are the Strongest Predictor of Response to Belimumab after Twelve Months of Therapy

Characterization of B- and T-Cell Compartment and B-Cell Related Factors Belonging to the TNF/TNFR Superfamily in Patients With Clinically Active Systemic Lupus Erythematosus: Baseline BAFF Serum Levels Are the Strongest Predictor of Response to Belimumab after Twelve Months of Therapy

Background: Patients with systemic lupus erythematosus (SLE) show increased serum levels of tumor necrosis factor (TNF)/TNF receptor (R) superfamily member, e.g. BAFF (B lymphocyte stimulator). Belimumab, a monoclonal antibody against soluble BAFF, is used for treatment of SLE. Although B cells are...

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Main Authors: Silvia Piantoni (Author), Francesca Regola (Author), Stefania Masneri (Author), Michele Merletti (Author), Torsten Lowin (Author), Paolo Airò (Author), Angela Tincani (Author), Franco Franceschini (Author), Laura Andreoli (Author), Georg Pongratz (Author)
Format: Book
Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
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3rd Floor Main Library

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