Investigation of the human metabolism and disposition of the prolyl hydrolase inhibitor daprodustat using IV microtracer with Entero‐Test bile string

• Prif Awduron: Guoying Tai (Awdur), Fangming Xia (Awdur), Cathy Chen (Awdur), Adrian Pereira (Awdur), Jill Pirhalla (Awdur), Xiusheng Miao (Awdur), Graeme Young (Awdur), Claire Beaumont (Awdur), Liangfu Chen (Awdur)
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• Cyhoeddwyd: Wiley, 2023-12-01T00:00:00Z.
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Abstract Daprodustat is an oral small molecule hypoxia‐inducible factor (HIF) prolyl hydroxylase inhibitor (PHI) approved in Japan and the United States for the treatment of anemia associated with chronic kidney disease. This phase 1, nonrandomized, 2‐period, crossover study in 6 healthy men charact...