Modulating effects of RAMPs on signaling profiles of the glucagon receptor family

• Ngā kaituhi matua: Lijun Shao (Author), Yan Chen (Author), Shikai Zhang (Author), Zhihui Zhang (Author), Yongbing Cao (Author), Dehua Yang (Author), Ming-Wei Wang (Author)
• Hōputu: Pukapuka
• I whakaputaina: Elsevier, 2022-02-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Receptor activity-modulating proteins (RAMPs) are accessory molecules that form complexes with specific G protein-coupled receptors (GPCRs) and modulate their functions. It is established that RAMP interacts with the glucagon receptor family of GPCRs but the underlying mechanism is poorly understood...