Increased glycolysis affects β-cell function and identity in aging and diabetes
Objective: Age is a risk factor for type 2 diabetes (T2D). We aimed to elucidate whether β-cell glucose metabolism is altered with aging and contributes to T2D. Methods: We used senescence-accelerated mice (SAM), C57BL/6J (B6) mice, and ob/ob mice as aging models. As a diabetes model, we used db/db...
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Main Authors: | Naoya Murao (Author), Norihide Yokoi (Author), Harumi Takahashi (Author), Tomohide Hayami (Author), Yasuhiro Minami (Author), Susumu Seino (Author) |
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Format: | Book |
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Elsevier,
2022-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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