The TSPO-specific Ligand PK11195 Protects Against LPS-Induced Cognitive Dysfunction by Inhibiting Cellular Autophagy

• Päätekijät: Nannan Lan (Tekijä), Yongxin Liu (Tekijä), Zhaodong Juan (Tekijä), Rui Zhang (Tekijä), Baoyu Ma (Tekijä), Keliang Xie (Tekijä), Lina Sun (Tekijä), Hao Feng (Tekijä), Meng Sun (Tekijä), Jianfeng Liu (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Perioperative neurocognitive disorders (PND) is a common postoperative neurological complication. Neuroinflammation is a major cause that leads to PND. Autophagy, an intracellular process of lysosomal degradation, plays an important role in the development and maintenance of nervous system. PK11195...