Lysosome activable polymeric vorinostat encapsulating PD-L1KD for a combination of HDACi and immunotherapy

• Główni autorzy: Fengkun Lu (Autor), Lei Hou (Autor), Sizhen Wang (Autor), Yingjie Yu (Autor), Yunchang Zhang (Autor), Linhong Sun (Autor), Chen Wang (Autor), Zhiqiang Ma (Autor), Feng Yang (Autor)
• Format: Książka
• Wydane: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

PD-1/PD-L1 blocking therapy has become one of the most promising methods in the field of tumor treatment. However, it encounters the challenge of immune escape due to the exhaustion of T cells. Studies have shown that the epigenetic regulation drug histone deacetylase inhibitor (HDACi) may be able t...