Molecular modeling and analysis of the 3D pharmacophore structure of the selective PI3K-α inhibitors as antitumor agents

• প্রধান লেখক: Jovanović Milan (লেখক), Nikolić Katarina (লেখক), Gagić Žarko (লেখক), Agbaba Danica (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Pharmaceutical Association of Serbia, Belgrade, Serbia, 2018-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The importance of the activation of phosphatidylinositol-3-kinase (PI3K) in the processes of tumor cell formation and growth has brought great interest in the development of new antitumor drugs that inhibit the PI3K-Akt signaling pathway. Recent studies have shown that in most tumors the activity of...