Mitochondrial-Lysosomal Axis in Acetaminophen Hepatotoxicity

• मुख्य लेखकों: Anna Moles (लेखक), Sandra Torres (लेखक), Anna Baulies (लेखक), Carmen Garcia-Ruiz (लेखक), Jose C. Fernandez-Checa (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Acetaminophen (APAP) toxicity is the most common cause of acute liver failure and a major indication for liver transplantion in the United States and Europe. Although significant progress has been made in understanding the molecular mechanisms underlying APAP hepatotoxicity, there is still an urgent...