Activation of a non-neuronal cholinergic system in visceral white adipose tissue of obese mice and humans

• Main Authors: Ilenia Severi (Author), Jessica Perugini (Author), Chiara Ruocco (Author), Lara Coppi (Author), Silvia Pedretti (Author), Eleonora Di Mercurio (Author), Martina Senzacqua (Author), Maurizio Ragni (Author), Gabriele Imperato (Author), Alessandra Valerio (Author), Nico Mitro (Author), Maurizio Crestani (Author), Enzo Nisoli (Author), Antonio Giordano (Author)
• Format: Book
• Published: Elsevier, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and objectives: Since white adipose tissue (WAT) lacks parasympathetic cholinergic innervation, the source of the acetylcholine (ACh) acting on white adipocyte cholinergic receptors is unknown. This study was designed to identify ACh-producing cells in mouse and human visceral WAT and to...