Inducing cyclooxygenase-2 expression, prostaglandin E2 and prostaglandin F2α production of human dental pulp cells by activation of toll-like receptor-3, mitogen-activated protein kinase kinase/extracellular signal-regulated kinase and p38 signaling

Background/purpose: Bacterial infection was the major etiology for pulpal/root canal infection. This study aimed to investigate the activation of toll-like receptor-3 (TLR) on cyclooxygenase-2 (COX-2) expression and prostaglandin E2 (PGE2) and PGF2α production of human dental pulp cells (HDPCs) and...

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Main Authors: Mei-Chi Chang (Author), Ju-Hui Wu (Author), Shyuan-Yow Chen (Author), Yung-Ting Hsu (Author), Sin-Yuet Yeung (Author), Yu-Hwa Pan (Author), Jiiang-Huei Jeng (Author)
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Publicado em: Elsevier, 2024-04-01T00:00:00Z.
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