Water-extracted branch of Cinnamomum cassia promotes lung cancer cell apoptosis by inhibiting pyruvate dehydrogenase kinase activity

• Main Authors: Eun-Ji Lee (Author), Tae-Wook Chung (Author), Jung-Hee Lee (Author), Bo-Sung Kim (Author), Eun-Yeong Kim (Author), Syng-Ook Lee (Author), Ki-Tae Ha (Author)
• Format: Book
• Published: Elsevier, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cinnamomum cassia Blume has been widely reported as the anti-tumor agent. However, the precise mechanism underlying its pro-apoptotic action is still not clear. Restraining aerobic glycolysis through suppression of pyruvate dehydrogenase kinase (PDHK) is a promising strategy for cancer inhibition. I...