Intra-articular delivery of flurbiprofen sustained release thermogel: improved therapeutic outcome of collagenase II-induced rat knee osteoarthritis

• Main Authors: Peinan Li (Author), Haokun Li (Author), Xiaohong Shu (Author), Moli Wu (Author), Jia Liu (Author), Tangna Hao (Author), Hongxia Cui (Author), Lianjie Zheng (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Knee osteoarthritis (OA) is a common degenerative disease. Intra-articular administration of flurbiprofen is frequently employed in clinic to treat OA, while repeated injections are required because of the limited effective duration. To improve therapeutic outcome and prolong the treatment interval,...