A Valid Bisphosphonate Modified Calcium Phosphate-Based Gene Delivery System: Increased Stability and Enhanced Transfection Efficiency In Vitro and In Vivo

• Những tác giả chính: Ming Zhao (Tác giả), Ji Li (Tác giả), Dawei Chen (Tác giả), Haiyang Hu (Tác giả)
• Định dạng: Sách
• Được phát hành: MDPI AG, 2019-09-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Calcium phosphate (CaP) nanoparticles, as a promising vehicle for gene delivery, have been widely used owing to their biocompatibility, biodegradability and adsorptive capacity for nucleic acids. Unfortunately, their utility in vivo has been profoundly restricted due to numerous technical barriers s...