Effect of Hemodialysis on Hepatic Cytochrome P450 Functional Expression

• Main Authors: Josée Michaud (Author), Thomas D. Nolin (Author), Judith Naud (Author), Mélina Dani (Author), Jean-Philippe Lafrance (Author), Francois A. Leblond (Author), Jonathan Himmelfarb (Author), Vincent Pichette (Author)
• Format: Book
• Published: Elsevier, 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cytochrome P450 (CYP) functional expression is reduced in uremia and normalized after restoration of kidney function via transplantation. The aim of this study was to evaluate the effect of conventional hemodialysis on the functional expression of CYP1A, 2C, and 3A. We also investigated the role of...