Adiporedoxin, an upstream regulator of ER oxidative folding and protein secretion in adipocytes

• Hauptverfasser: Mark P. Jedrychowski (VerfasserIn), Libin Liu (VerfasserIn), Collette J. Laflamme (VerfasserIn), Kalypso Karastergiou (VerfasserIn), Tova Meshulam (VerfasserIn), Shi-Ying Ding (VerfasserIn), Yuanyuan Wu (VerfasserIn), Mi-Jeong Lee (VerfasserIn), Steven P. Gygi (VerfasserIn), Susan K. Fried (VerfasserIn), Paul F. Pilch (VerfasserIn)
• Format: Buch
• Veröffentlicht: Elsevier, 2015-11-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Objective: Adipocytes are robust protein secretors, most notably of adipokines, hormone-like polypeptides, which act in an endocrine and paracrine fashion to affect numerous physiological processes such as energy balance and insulin sensitivity. To understand how such proteins are assembled for secr...