Phenotypic screen of early-developing larvae of the blood fluke, schistosoma mansoni, using RNA interference.

• Main Authors: M M Mourão (Author), Nathalie Dinguirard (Author), Glória R Franco (Author), Timothy P Yoshino (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2009-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

RNA interference (RNAi) represents the only method currently available for manipulating gene-specific expression in Schistosoma spp., although application of this technology as a functional genomic profiling tool has yet to be explored. In the present study 32 genes, including antioxidants, transcri...