Targeting extracellular matrix through phytochemicals: a promising approach of multi-step actions on the treatment and prevention of cancer

• Main Authors: Dan Liang (Author), Lu Liu (Author), Yunjie Zhao (Author), Zhenyi Luo (Author), Yadi He (Author), Yanping Li (Author), Shiyun Tang (Author), Jianyuan Tang (Author), Nianzhi Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Extracellular matrix (ECM) plays a pivotal and dynamic role in the construction of tumor microenvironment (TME), becoming the focus in cancer research and treatment. Multiple cell signaling in ECM remodeling contribute to uncontrolled proliferation, metastasis, immune evasion and drug resistance of...