Simple and Fast DNA Based Sensor System for Screening of Small-Molecule Compounds Targeting Eukaryotic Topoisomerase 1

<b>Background</b>: Eukaryotic topoisomerase 1 is a potential target of anti-parasitic and anti-cancer drugs. Parasites require topoisomerase 1 activity for survival and, consequently, compounds that inhibit topoisomerase 1 activity may be of interest. All effective topoisomerase 1 drugs...

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Main Authors: Kamilla Vandsø Petersen (Author), Asier Selas (Author), Kirstine Mejlstrup Hymøller (Author), Karol Mizielinski (Author), Maria Thorsager (Author), Magnus Stougaard (Author), Concepcion Alonso (Author), Francisco Palacios (Author), Yolanda Pérez-Pertejo (Author), Rosa M. Reguera (Author), Rafael Balaña-Fouce (Author), Birgitta R. Knudsen (Author), Cinzia Tesauro (Author)
Format: Book
Published: MDPI AG, 2021-08-01T00:00:00Z.
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Call Number: A1234.567
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