Mid1 promotes synovitis in rheumatoid arthritis via ubiquitin-dependent post-translational modification

• Main Authors: Liman Lin (Author), Zhiwen Huang (Author), Wenjuan Li (Author), Xinxin Liu (Author), Xinlu Li (Author), Shupei Gao (Author), Jun Chen (Author), Chenxi Yang (Author), Xinwen Min (Author), Handong Yang (Author), Quan Gong (Author), Yingying Wei (Author), Shenghao Tu (Author), Xiaoquan Rao (Author), Ziyang Zhang (Author), Lingli Dong (Author), Jixin Zhong (Author)
• Format: Book
• Published: Elsevier, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Current anti-rheumatic drugs are primarily modulating immune cell activation, yet their effectiveness remained suboptimal. Therefore, novel therapeutics targeting alternative mechanisms, such as synovial activation, is urgently needed. Objectives: To explore the role of Midline-1 (Mid1...