Development of a mouse monoclonal antibody cocktail for post-exposure rabies prophylaxis in humans.

• Main Authors: Thomas Müller (Author), Bernhard Dietzschold (Author), Hildegund Ertl (Author), Anthony R Fooks (Author), Conrad Freuling (Author), Christine Fehlner-Gardiner (Author), Jeannette Kliemt (Author), Francois X Meslin (Author), Richard Franka (Author), Charles E Rupprecht (Author), Noël Tordo (Author), Alexander I Wanderler (Author), Marie Paule Kieny (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As the demand for rabies post-exposure prophylaxis (PEP) treatments has increased exponentially in recent years, the limited supply of human and equine rabies immunoglobulin (HRIG and ERIG) has failed to provide the required passive immune component in PEP in countries where canine rabies is endemic...