Formulation and optimization of duloxetine hydrochloride buccal films: in vitro and in vivo evaluation
Duloxetine hydrochloride (DH) is a serotonin-norepinephrine reuptake inhibitor (SSNRI) indicated for the treatment of depression. Duloxetine suffers from reduced oral bioavailability (≈50%) due to hepatic metabolism. This study aims to develop DH buccoadhesive films to improve its bioavailability. D...
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Format: | Book |
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Taylor & Francis Group,
2017-01-01T00:00:00Z.
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A1234.567 |
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