Formulation and optimization of duloxetine hydrochloride buccal films: in vitro and in vivo evaluation

Duloxetine hydrochloride (DH) is a serotonin-norepinephrine reuptake inhibitor (SSNRI) indicated for the treatment of depression. Duloxetine suffers from reduced oral bioavailability (≈50%) due to hepatic metabolism. This study aims to develop DH buccoadhesive films to improve its bioavailability. D...

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Main Authors: Amr Mostafa El Sharawy (Author), Marwa Hassan Shukr (Author), Ahmed Hassen Elshafeey (Author)
Format: Book
Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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