Pulmonary Delivery of Favipiravir in Rats Reaches High Local Concentrations without Causing Oxidative Lung Injury or Systemic Side Effects

• প্রধান লেখক: Ozlem Akbal-Dagistan (লেখক), Mustafa Sevim (লেখক), Leyla Semiha Sen (লেখক), Nur Sena Basarir (লেখক), Meltem Culha (লেখক), Aybige Erturk (লেখক), Hanan Fael (লেখক), Engin Kaptan (লেখক), Serap Sancar (লেখক), Lutfiye Mulazimoglu Durmusoglu (লেখক), Berrak C. Yegen (লেখক), Ayca Yildiz-Pekoz (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2022-11-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Favipiravir displays a rapid viral clearance, a high recovery rate and broad therapeutic safety; however, its oral administration was associated with systemic side effects in susceptible patients. Considering that the pulmonary route could provide a high drug concentration, and a safer application w...