Concomitant inhibition of PI3K/mTOR signaling pathways boosts antiproliferative effects of lanreotide in bronchopulmonary neuroendocrine tumor cells

• Autori principali: Claus von Hessert-Vaudoncourt (Autore), Sara Lelek (Autore), Christina Geisler (Autore), Teresa Hartung (Autore), Vanessa Bröker (Autore), Franziska Briest (Autore), Liliana Mochmann (Autore), Fabian Jost-Brinkmann (Autore), Dagmar Sedding (Autore), Joana Benecke (Autore), Helma Freitag (Autore), Sebastian Wolfshöfer (Autore), Hedwig Lammert (Autore), Svenja Nölting (Autore), Michael Hummel (Autore), Jörg Schrader (Autore), Patricia Grabowski (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2024-02-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Introduction: Somatostatin analogues (SSAs) are commonly used in the treatment of hormone hypersecretion in neuroendocrine tumors (NETs), however the extent to which they inhibit proliferation is much discussed.Objective: We studied the antiproliferative effects of novel SSA lanreotide in bronchopul...