Panax notoginseng saponins promote liver regeneration through activation of the PI3K/AKT/mTOR cell proliferation pathway and upregulation of the AKT/Bad cell survival pathway in mice

• Main Authors: Hua Zhong (Author), Hao Wu (Author), He Bai (Author), Menghao Wang (Author), Jian Wen (Author), Jianping Gong (Author), Mingyong Miao (Author), Fangchao Yuan (Author)
• Format: Book
• Published: BMC, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Backgroud The regenerative capacity of the liver is crucial for the host to survive after serious hepatic injuries, tumor resection, or living donor liver transplantation. Panax notoginseng saponins (PNS) have been reported to exert protective effects during organ injuries. The present stud...