Characterization of the Proinflammatory Profile of Synovial Fluid-Derived Exosomes of Patients with Osteoarthritis

• Main Authors: Rossana Domenis (Author), Rossella Zanutel (Author), Federica Caponnetto (Author), Barbara Toffoletto (Author), Adriana Cifù (Author), Cinzia Pistis (Author), Paolo Di Benedetto (Author), Araldo Causero (Author), Massimo Pozzi (Author), Fabrizio Bassini (Author), Martina Fabris (Author), Kayvan R. Niazi (Author), Patrick Soon-Shiong (Author), Francesco Curcio (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The purpose of this study is to characterize synovial fluid- (SF-) derived exosomes of patients with gonarthrosis comparing two methods of isolation and to investigate their immune regulatory properties. Extracellular vesicles (EVs) have been isolated from inflamed SF by polymer precipitation method...