Immunity to Lutzomyia intermedia saliva modulates the inflammatory environment induced by Leishmania braziliensis.

• Main Authors: Tatiana R de Moura (Author), Fabiano Oliveira (Author), Gabriele C Rodrigues (Author), Marcia W Carneiro (Author), Kiyoshi F Fukutani (Author), Fernanda O Novais (Author), José Carlos Miranda (Author), Manoel Barral-Netto (Author), Claudia Brodskyn (Author), Aldina Barral (Author), Camila I de Oliveira (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: During blood feeding, sand flies inject Leishmania parasites in the presence of saliva. The types and functions of cells present at the first host-parasite contact are critical to the outcome on infection and sand fly saliva has been shown to play an important role in this setting. Herei...