In Vitro Antioxidant and Pancreatic Anticancer Activity of Novel 5-Fluorouracil-Coumarin Conjugates

• Autors principals: Sonia López (Autor), Ignacio Gracia (Autor), Rodrigo Plaza-Pedroche (Autor), Juan Francisco Rodríguez (Autor), José Manuel Pérez-Ortiz (Autor), Julián Rodríguez-López (Autor), María Jesús Ramos (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2022-10-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Molecular hybridization consists of the combination of two or more non-identical pharmacophores in a single molecule. It has emerged as a promising strategy that allows the design of molecular frameworks with enhanced activity and affinity compared to their parent drugs. In this work, two novel hybr...