Successful strategy of comprehensive pre-implantation genetic testing for Duchenne muscular dystrophy and chromosome balance using karyomapping and fluorescent PCR

• Main Authors: Suchada Mongkolchaipak (Author), Sirivipa Piyamongkol (Author), Chutithep Teekaput (Author), Rungthiwa Sirapat (Author), Wanwisa Suriya (Author), Tawiwan Pantasri (Author), Theera Tongsong (Author), Wirawit Piyamongkol (Author)
• Format: Book
• Published: IMR Press, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Duchenne muscular dystrophy (DMD) is major childhood muscular dystrophy. Pre-implantation genetic testing (PGT) is an alternative to prenatal diagnosis. This study performed SNP microarray with karyomapping PGT of DMD in comparison to PCR-based techniques for validation. Methods: Two fam...