Amphiregulin Exerts Proangiogenic Effects in Developing Murine Lungs

• Main Authors: Shyam Thapa (Author), Nithyapriya Shankar (Author), Amrit Kumar Shrestha (Author), Monish Civunigunta (Author), Amos S. Gaikwad (Author), Binoy Shivanna (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Interrupted lung angiogenesis is a hallmark of bronchopulmonary dysplasia (BPD); however, druggable targets that can rescue this phenotype remain elusive. Thus, our investigation focused on amphiregulin (Areg), a growth factor that mediates cellular proliferation, differentiation, migration, surviva...