Anticancer activity and toxicity of new quaternary ammonium geldanamycin derivative salts and their mixtures with potentiators
Geldanamycin (GDM) has been modified by different type neutral/acidic/basic substituents (1-7) and by quinuclidine motif (8), transformed into ammonium salts (9-13) at C(17). These compounds have been characterised by spectroscopic and x-ray methods. Derivative 8 shows better potency than GDM in MCF...
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Main Authors: | , , , , , , , , |
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Format: | Book |
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Taylor & Francis Group,
2021-01-01T00:00:00Z.
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A1234.567 |
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