Anticancer activity and toxicity of new quaternary ammonium geldanamycin derivative salts and their mixtures with potentiators

Geldanamycin (GDM) has been modified by different type neutral/acidic/basic substituents (1-7) and by quinuclidine motif (8), transformed into ammonium salts (9-13) at C(17). These compounds have been characterised by spectroscopic and x-ray methods. Derivative 8 shows better potency than GDM in MCF...

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Main Authors: Natalia Skrzypczak (Author), Krystian Pyta (Author), Piotr Ruszkowski (Author), Przemysław Mikołajczak (Author), Małgorzata Kucińska (Author), Marek Murias (Author), Maria Gdaniec (Author), Franz Bartl (Author), Piotr Przybylski (Author)
Format: Book
Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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