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Ferritin nanoconjugates guide trastuzumab brain delivery to promote an antitumor response in murine HER2 + breast cancer brain metastasis

Brain metastasis (BM) represents a clinical challenge for patients with advanced HER2 + breast cancer (BC). The monoclonal anti-HER2 antibody trastuzumab (TZ) improves survival of BC patients, but it has low central nervous system penetrance, being ineffective in treating BM. Previous studies showed...

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Main Authors: Marta Sevieri (Author), Serena Mazzucchelli (Author), Linda Barbieri (Author), Stefania Garbujo (Author), Stephana Carelli (Author), Arianna Bonizzi (Author), Federica Rey (Author), Camilla Recordati (Author), Matteo Recchia (Author), Raffaele Allevi (Author), Leopoldo Sitia (Author), Carlo Morasso (Author), Pietro Zerbi (Author), Davide Prosperi (Author), Fabio Corsi (Author), Marta Truffi (Author)
Format: Book
Published: Elsevier, 2023-10-01T00:00:00Z.
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