Nanoparticle delivery of a tetravalent E protein subunit vaccine induces balanced, type-specific neutralizing antibodies to each dengue virus serotype.

• প্রধান লেখক: Stefan W Metz (লেখক), Ashlie Thomas (লেখক), Alex Brackbill (লেখক), Yi Xianwen (লেখক), Michele Stone (লেখক), Katie Horvath (লেখক), Michael J Miley (লেখক), Chris Luft (লেখক), Joseph M DeSimone (লেখক), Shaomin Tian (লেখক), Aravinda M de Silva (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Public Library of Science (PLoS), 2018-09-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Dengue virus (DENV) is the causative agent of dengue fever and dengue hemorrhagic shock syndrome. Dengue vaccine development is challenging because of the need to induce protection against four antigenically distinct DENV serotypes. Recent studies indicate that tetravalent DENV vaccines must induce...