Excretion connection VMA-99-82 - a novel adenine having antiviral activity

• Main Authors: L. A. Smirnova (Author), E. A. Suchkov (Author), A. F. Ryabukha (Author), K. A. Kuznetsov (Author), A. A. Ozerov (Author), A. V. Karavaev (Author)
• Format: Book
• Published: LLC "Publisher OKI", 2013-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the study of excretion of the drug established that VMA-99-82 detected in the urine for at least 72 hours of the study. Renal clearance was 0.936 ml/hr, extrarenal - 666.04 ml/h by intravenous route of administration, 1.8 ml/hr and 1009.72 ml/h, respectively, by the oral route of administration....