Activation of NR1H3 attenuates the severity of septic myocardial injury by inhibiting NLRP3 inflammasome

• প্রধান লেখক: Chao Deng (লেখক), Qiong Liu (লেখক), Huadong Zhao (লেখক), Lu Qian (লেখক), Wangrui Lei (লেখক), Wenwen Yang (লেখক), Zhenxing Liang (লেখক), Ye Tian (লেখক), Shaofei Zhang (লেখক), Changyu Wang (লেখক), Ying Chen (লেখক), Yang Yang (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Wiley, 2023-05-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Most sepsis deaths are due to the development of multiple organ failure, in which heart failure is a recognized manifestation of sepsis. To date, the role of liver X receptors α (NR1H3) in sepsis is still uncertain. Here, we hypothesized that NR1H3 mediates multiple essential sepsis‐related...