γδTDEs: An Efficient Delivery System for miR-138 with Anti-tumoral and Immunostimulatory Roles on Oral Squamous Cell Carcinoma

• Main Authors: Ling Li (Author), Shun Lu (Author), Xinhua Liang (Author), Bangrong Cao (Author), Shaoxin Wang (Author), Jian Jiang (Author), Huaichao Luo (Author), Shuya He (Author), Jinyi Lang (Author), Guiquan Zhu (Author)
• Format: Book
• Published: Elsevier, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, we sought to investigate the potential application of γδ T cell-derived extracellular vesicles (γδTDEs) as drug delivery system (DDS) for miR-138 in the treatment of oral squamous cell carcinoma (OSCC). Our data showed that overexpression of miR-138 in γδ T cells obtained miR-138-rich...