Inhibition of Circulating miR-194-5p Reverses Osteoporosis through Wnt5a/β-Catenin-Dependent Induction of Osteogenic Differentiation

• Main Authors: Bobin Mi (Author), Chenchen Yan (Author), Hang Xue (Author), Lang Chen (Author), Adriana C. Panayi (Author), Liangcong Hu (Author), Yiqiang Hu (Author), Faqi Cao (Author), Yun Sun (Author), Wu Zhou (Author), Yuan Xiong (Author), Guohui Liu (Author)
• Format: Book
• Published: Elsevier, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mesenchymal stem cells (MSCs) critically contribute to bone formation, and proper induction of osteogenic differentiation can lead to an increase in bone mass. In the present study, we reported that an increased miR-194-5p level in plasma is inversely related to the degree of bone formation in osteo...