Deciphering the multifaceted roles and clinical implications of 2-hydroxyglutarate in cancer
Increasing evidence indicates that 2-hydroxyglutarate (2HG) is an oncometabolite that drives tumour formation and progression. Due to mutations in isocitrate dehydrogenase (IDH) and the dysregulation of other enzymes, 2HG accumulates significantly in tumour cells. Due to its structural similarity to...
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Main Authors: | , , , , , , , |
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Format: | Book |
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Elsevier,
2024-11-01T00:00:00Z.
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A1234.567 |
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