Solid lipid nanoparticles of irbesartan: preparation, characterization, optimization and pharmacokinetic studies

• Main Authors: Deepthi Soma (Author), Zenab Attari (Author), Meka Sreenivasa Reddy (Author), Atmakuri Damodaram (Author), Kunnatur Balasundara Gupta Koteshwara (Author)
• Format: Book
• Published: Universidade de São Paulo, 2017-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT Irbesartan is an antihypertensive with limited bioavailability and solid lipid nanoparticles (SLN) is one of the approaches to improve bioavailability. Solid lipid nanoparticles were prepared using glyceryl monostearate by solvent emulsification method followed by probe sonication. Irbesart...