Imbalance of Circulatory T Follicular Helper and T Follicular Regulatory Cells in Patients with ANCA-Associated Vasculitis

• Main Authors: Ying Xu (Author), Hongmei Xu (Author), Yu Zhen (Author), Xueting Sang (Author), Hao Wu (Author), Cong Hu (Author), Zhanchuan Ma (Author), Miaomiao Yu (Author), Huanfa Yi (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Antineutrophil cytoplasmic antibody- (ANCA-) associated vasculitis (AAV) is characterized by small-vessel inflammation in association with autoantibodies. Balance between T follicular helper (Tfh) cells and T follicular regulatory (Tfr) cells is critical for humoral immune responses. Accumulating ev...