Nucleosides present on phlebotomine saliva induce immunossuppression and promote the infection establishment.

• Asıl Yazarlar: Vanessa Carregaro (Yazar), José M Ribeiro (Yazar), Jesus G Valenzuela (Yazar), Djalma L Souza-Júnior (Yazar), Diego L Costa (Yazar), Carlo J F Oliveira (Yazar), Laís A Sacramento (Yazar), Manuela S L Nascimento (Yazar), Cristiane M Milanezi (Yazar), Fernando Q Cunha (Yazar), João S Silva (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Public Library of Science (PLoS), 2015-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Sand fly saliva plays a crucial role in establishing Leishmania infection. We identified adenosine (ADO) and adenosine monophosphate (AMP) as active pharmacologic compounds present in Phlebotomus papatasi saliva that inhibit dendritic cell (DC) functions through a PGE2/IL 10-dependent mechanism.Here...