Polyfunctional T cell responses in children in early stages of chronic Trypanosoma cruzi infection contrast with monofunctional responses of long-term infected adults.
<h4>Background</h4>Adults with chronic Trypanosoma cruzi exhibit a poorly functional T cell compartment, characterized by monofunctional (IFN-γ-only secreting) parasite-specific T cells and increased levels of terminally differentiated T cells. It is possible that persistent infection an...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Book |
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Public Library of Science (PLoS),
2013-01-01T00:00:00Z.
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